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66 vs. 3.06 vs. 3.00 respectively, p = .043) and anti-S1RBD IgG (median OD450 2.33 vs. 1.6 vs. 0.91, respectively, p less then .001). By testing 48 subjects 6 months or above from discharge, a significant decrease of anti-NP IgG was observed (r -0.5838; p less then .0001), whereas anti-S1RBD IgG showed only a modest reduction (r -0.1507; p = .0647). Accordingly, 10 (21%) and 2 (4%) patients had a negative serological status for anti-NP and anti-S1RBD IgG, respectively; no association with clinical severity was found. I