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oups at all three time points. The fracture model with high consistency and reproducibility showed progressive post-traumatic osteoarthritic changes which could be improved by open reduction and internal fixation surgery and provided an alternative selection for investigating potential pathogenesis and pathology of post-traumatic osteoarthritis following fracture of acetabulum. The fracture model with high consistency and reproducibility showed progressive post-traumatic osteoarthritic changes which could be improved by open red