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We here explain a gene phrase regulation community consisting of many DNA methyltransferases each frequently changing its target sequence-specificity. Our object Helicobacter pylori, a bacterium in charge of most occurrence of tummy disease, carries a large and adjustable repertoire of sequence-specific DNA methyltransferases. By creating a dozen of single-gene knockout strains when it comes to methyltransferases, we revealed that they form a network controlling methylome, transcri
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