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In this population, there was an 81% increase in the risk of mortality among patients who received HCQ at any time during their hospital stay versus no HCQ exposure (OR 1.81, 95% CI 1.20-2.77, p = 0.01). In this retrospective analysis, we found that there was no benefit of administration of HCQ on mortality in COVID-19 patients. These results support recent changes to clinical trials that discourage the use of HCQ in COVID-19 patients. In this retrospective analysis, we found that there was no benefit of administration of HCQ on mortalit