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Among solid organ transplant recipients, donor CMV seropositive (D+), recipient seronegative (R-) status is associated with an increased risk of graft loss and mortality after kidney or lung transplant. Whether a similar relationship exists among liver transplant recipients (LTxR) is unknown. We assessed graft loss and mortality among adult LTxRs from 1/1/2010 to 3/14/2020 in the Organ Procurement and Transplantation Network (OPTN) database. We used multivariable mixed Cox proportional hazards regression to analyze the association of d