https://www.selleckchem.com/pr....oducts/zasocitinib.h
In this manuscript, we report the chemical synthesis and derivatization of an ortho-functionalized tetrachlorinated azobenzene diol. A 4'4-dimethoxytrityl (DMT) phosphoramidite was synthesized for its site-specific incorporation within the sense strand of an siRNA duplex to form ortho-functionalized tetrachlorinated azobenzene-containing siRNAs (Cl-siRNAzos). Compared to a non-halogenated azobenzene, ortho-functionalized tetrachlorinated azobenzenes are capable of red-shifting the π - π* transition from the ultraviolet (UV) port
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