https://www.selleckchem.com/products/PLX-4032.html
Recently, cell-based tissue engineering approaches using mesenchymal stem cells (MSCs) have been used to treat osteoarthritis (OA). However, the efficacy of human synovium-derived MSCs (hSD-MSCs) has not yet been tested in a canine model of OA. The purpose of this study was to investigate the therapeutic effects of intra-articular hSD-MSC injections in a canine OA model. Sixty beagles underwent surgical manipulation to induce OA and received intra-articular injection 4weeks after surgery. The dogs were divided into five groups (n=12) a