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Although ZnO NPs exhibited higher toxicity, as indicated by the NRRT50 values, both NPs affected similarly a wide range of the cellular parameters mentioned above. The latter parameters could constitute sensitive biomarkers in biomonitoring studies of terrestrial environment against nanoparticles.Clotrimazole (CLO) is an imidazole fungicide used in human and veterinary medicine for treating fungal infection. This study evaluated the changes in morphological, haematological and biochemical indices in Clarias gariepinus juveniles exposed to