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844), serum albumin concentration (X2, β' = -0.393), and CSF protein concentration (X3, β' = 0.098) were identified as the three variables that significantly predicted the dependent variable; Ŷ=2.356+0.024X1-0.059X2+0.044X3, with a coefficient of determination (R) of 0.874. As the CSF protein level is often unavailable, the model was redefined to include two variables-serum concentrations of VPA (X1, β' = 0.84 and serum albumin concentration (X2, β' = -0.359). Ŷ=1.706+0.024X1-0.039X2, R = 0.813. CONCLUSIONS Based on total VPA and serum