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Our hypothesis applies only to internalizing disorders. So, we predict that ketamine will be effective in simple phobia and (perhaps partially) in anorexia nervosa, but would make no such prediction about other disorders where neuroticism might also be important secondarily (e.g. attention deficit hyperactivity disorder and schizophrenia).A "silent epidemic" of oral diseases is afflicting older adults. Older adults develop coronal caries at "approximately one new cavity per year". Despite the rapidly growing older adult population, no rec