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BPA gets the prospective to induce hepatotoxicity via generation of ROS and oxidative tension. But, the mechanism of BPA caused oxidative anxiety and autophagy is still uncertain at molecular and cellular levels. This study is designed to elucidate the impact of BPA exposure (50 and 100 μM) in major rat hepatocytes. AMP kinase, an intracellular energy sensor and crucial regulator in cellular signaling had been discovered become tri