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We then improved the LINTAD system to attain ideal effectiveness in major human being T cells. The outcome showed that pulsed light stimulations can stimulate LINTAD automobile T cells with strong cytotoxicity against target cancer tumors cells, both in vitro and in vivo. Therefore, our LINTAD system can serve as an efficient tool to noninvasively control gene activation and activate inducible automobile T cells for precision cancer tumors
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