https://www.selleckchem.com/pr....oducts/gcn2-in-1.htm
No differences in the rates of pubertal entry were seen between girls and boys after data harmonization. The broad range of ages at pubertal entry for children with constitutional delay challenges the concept that constitutional delay is merely an extreme of normal variation. Discussions with patients and families about management should consider the possibility that some children may need to wait years after presentation until puberty starts. The broad range of ages at pubertal entry for children with constitutional delay challenges