https://www.selleckchem.com/pr....oducts/Methazolaston
A chemoselective C(sp2 )-C(sp2 ) coupling of sufficiently electron-deficient fluorinated arenes and functionalized N-aryl-N'-silyldiazenes as masked aryl nucleophiles is reported. The fluoride-promoted transformation involves the in situ generation of the aryl nucleophile decorated with various sensitive functional groups followed by a stepwise nucleophilic aromatic substitution (SN Ar). These reactions typically proceed at room temperature within minutes. This catalytic process allows for the functionalization of both coupling p
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