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Treating ADHD Without Medication Many people with ADHD discover that treating their symptoms without medication is effective. Combining psychotherapy, behavior change and natural remedies is often the best solution. Medications like methylphenidate increase certain brain chemicals that regulate attention and impulses. Nonstimulants, such as Guanfacine or atomoxetine, are also available. Psychotherapy, exercise and good sleep habits can also help. Certain people with ADHD suffer from coexis