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Additionally, the reporter signal could possibly be recognized from both cellular lysates and real time cells. The alert standard of our reporter responded to the co-expression of SUMOylation or deSUMOylation enzymes by several fold, showing powerful potency of this reporter. The reporter was active in numerous cell kinds, including ATDC5 cells, that have chondrogenic potential. Finally, utilizing this reporter, we unveiled a extracellular sign conditions that i