https://www.selleckchem.com/pr....oducts/vx803-m4344.h
Purpose of review This review summarizes recent progress in our understanding how environmental adjuvants promote the development of asthma. Recent findings Asthma is a heterogeneous set of lung pathologies with overlapping features. Human studies and animal models suggest that exposure to different environmental adjuvants activate distinct immune pathways, which in turn give rise to distinct forms, or endotypes, of allergic asthma. Depending on their concentrations, inhaled TLR ligands can activate either type 2 inflammation, or Th