https://www.selleckchem.com/pr....oducts/chir-99021-ct
Finally, the substrate reduction drug L-cycloserine significantly decreased the level of the pro-apoptotic ceramide 180. These data demonstrate the value of AAV-based combination therapy for Krabbe disease. However, they also suggest that other therapies or co-morbidities must be taken into account before AAV-mediated gene therapy is considered for human therapeutic trials.Chimeric antigen receptor (CAR) T cell therapy has yielded unprecedented outcomes in some patients with hematological malignancies; however, inhibition