https://www.selleckchem.com/pr....oducts/8-oh-dpat-8-h
The prophage BTP1 is highly conserved among strains of the pathogenic lineage Salmonella Typhimurium (S. Typhimurium) ST313. We aimed to analyze the role of BTP1 and the gene bstA (BTP1-encoded) in virulence of S. Typhimurium D23580, the ST313 lineage 2 reference strain. The deletion mutant D23580ΔbstA showed significantly higher replication and survival rates within human derived THP-1 macrophages than the WT-strain, while the mutant strain ΔBTP1, lacking the full prophage, did not significantly differ from the WT. Int