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Treatment of Add in Adults Treatment of Add in adults usually involves some combination of medication, life-skills training and psychotherapy. Most patients respond best to stimulant medications like methylphenidate (Ritalin) and amphetamines, like lisdexamphetamine (Adderall) or extended-release mixed amphetamine salts (Adderall XR). The effects of stimulants can raise heart rate and blood pressure. Non-stimulants, like atomoxetine and bupropion, also help to reduce ADHD sy