https://www.selleckchem.com/pr....oducts/tasquinimod.h
Eventually, using real-time-PCR, the CREB mRNA changes in the hippocampus were evaluated. Posttraining MOR (7.5 mg/kg-i.p.) impaired IA memory (P0.001). The pre-test injection of similar doses of morphine recovered the morphine-induced memory impairment (P0.001). The pre-test PTZ impaired the IA memory recall (P0.001); however, the pre-test PTZ along with morphine STD potentiated the morphine-induced STD (P0.001). Alterations in CREB mRNA were observed in all groups. No difference was seen in the locomotor activity.
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