https://www.selleckchem.com/pr....oducts/NVP-AUY922.ht
79. Under realistic testing conditions, information theory suggested a higher threshold, OD1.5 versus OD0.6. Increasing the diagnostic threshold improved the global information value, the value of a positive test and the noise content with only a minute change in the negative test value. Our information theoretic approach suggested that the current FDA approved cutoff (OD0.4) is overly permissive leading to loss of test value and injection of noise into an already complex diagnostic dilemma. Because our approach is purely
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