https://www.selleckchem.com/pr....oducts/Cyclopamine.h
s in the 3'-UTR of Slit2 abolish this inhibition. Together, these data demonstrate a pro-fibrotic role of miR-424 in TGF-β1-induced HLF differentiation. It functions as a positive feed-back regulator of the TGF-β1 signaling pathway by reducing expression of the negative regulator Slit2. Thus, targeting miR-424 may provide a new therapeutic strategy to prevent myofibroblast differentiation and IPF progression.In the present study we aimed firstly to assess the resistance of a set of yeasts, isolated from the black olive pomace, to va
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