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97, 95%CI 1.05-15.0, value = 0.04). Compared to CS, EGDS shortened the procedural time of ERCP in B-II patients. Compared to CS, EGDS shortened the procedural time of ERCP in B-II patients. Endoscopic ultrasound-guided fine needle biopsy (EUS-FN has emerged as a safe, efficacious alternative to fine needle aspiration (FNA) for tissue acquisition. EUS-FNB is reported to have higher diagnostic yield while preserving specimen tissue architecture. However, data on the optimal method of EUS-FNB specimen processing is limited. To evaluate