https://www.selleckchem.com/pr....oducts/ly3537982.htm
To review the impact of the timeliness of antibiotic therapy on the outcome of patients with sepsis or septic shock. We searched MEDLINE, EMBASE, the Cochrane Library, Web of Science, Open-SIGLE databases, ClinicalTrials.gov and the metaRegister of Controlled Trials on July 27, 2020 for relevant studies on the timing of antibiotic therapy in adult patients with sepsis or septic shock. The primary outcome measure was all-cause crude or adjusted mortality at reported time points. We included 35 sepsis studies involving 154,330 patients.