https://www.selleckchem.com/pr....oducts/crt-0105446.h
Dry eye is a common sight-impairing painful disorder characterized by disruption of the pre-ocular tear film whose integrity is required for ~70% of the eye's refractive power. A universal feature of clinical dry eye is hyperosmolarity of the tears resulting from their accelerated evaporation due to dysfunction of tear- and oil-producing ocular glands. A key adaptive response to dryness/hyperosmolarity is release of tear-stabilizing mucin by conjunctival goblet cells. Yet the mechanisms mediating their response to hyperosmolarity re