https://www.selleckchem.com/pr....oducts/pf-06463922.h
Curcumin significantly improved blood glucose level, redox status, cellular stress, and decreased INF-γ and Bax levels, down-regulated GRP78 and ATF-4 expression, meanwhile, up-regulated Bcl2 and ChAT expression in hippocampus. Histological findings proved the biochemical and molecular findings. Our results support curcumin as a potential neuro-protective agent against diabetes induced hippocampal neurodegeneration.Hyperglycemia has been shown to counterbalance the beneficial effects of tissue plasminogen activator (tPA) and increas
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