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Swelling-induced strain was highly heterogeneous in AF rings, where unfavorable circumferential strains had been seen in the inner AF and tensile circumferential strains were observed in the outer AF. Radial strains in AF bands had been an order of magnitude higher than circumferential strains. Restricting fluid movement and then the outer AF periphery reduced the swelling of the inner AF. Inflammation of intact discs affected both NP and AF inflammation behaviors, where NP moisture diminished by 60%. A