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832, p 0.01). Using multivariate binary logistic regression, 2 models estimating whether the vessel met the size criteria (lumen size of 160-240 μm) were generated with an area under the receiver operating characteristic curve of 0.761 for the upper limit and 0.747 for the lower limit. The U-Net-based image analysis method could streamline the experimental approach. The U-Net-based image analysis method could streamline the experimental approach. Social isolation is detrimental to late-life health outcomes. Although ob