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Chronic burden was associated with 1.85 higher odds (95% confidence interval = 1.11-3.09) of MetS. Sleep characteristics were not associated with MetS. There was no evidence that sleep mediated the chronic burden-MetS relation. Burden of chronic stress may be an emerging novel risk factor for both poor sleep and MetS. Burden of chronic stress may be an emerging novel risk factor for both poor sleep and MetS. Within the field of psychoneuroimmunology, much attention has been given to immune dysregulation and its impact on cognitive functioni
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