Mesothelioma Settlements The majority of mesothelioma cases result in settlements, not the verdict of a jury. Defense attorneys take many factors into consideration during negotiations which include treatment costs and lost income. The compensation from a lawsuit for mesothelioma can help the victim and their families. Lawsuits also hold those accountable for asbestos exposure. The average settlement for mesothelioma is about $1 million. Compensation for Pain and Suffering Compensation may be offered to victims of mesothelioma or their famili