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001), and for PPIs alone (OR = 1.27; CI, 1.17-1.38; P less then 0.001), but not H2As alone (OR = 1.18; CI, 0.92-1.53; P = 0.2). We found no evidence of blood iron stores mediating this association. The association of PPI, and possibly H2A, consumption with RLS independent of blood iron status and other factors which contribute to RLS risk suggest the need to re-evaluate use of PPI/H2A in populations at particular risk for RLS. Safety and efficacy of antithrombotic regimens in patients with atrial fibrillation (AF) undergoing percutaneous c