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The management of customers with severe myocardial infarction difficult by cardiogenic shock is highly complex, and outcomes may rely on the time of medical center admission and subsequent intervention (ie, ON-hours versus OFF-hours). The CULPRIT-SHOCK test (Culprit Lesion Only PCI Versus Multivessel PCI in Cardiogenic Shock) demonstrated superior result for culprit-lesion-only versus instant multivessel percutaneous coronary input in customers providing with severe myocardial infar