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How Does Medication For ADHD Work? ADHD medication can help children and adults improve their ability focus and control their impulses. It also helps them become more organized. Your doctor will decide the most appropriate medication for your child in consultation with you. Stimulants are the first line treatment for ADHD. They increase the levels of two brain chemicals known as norepinephrine and dopamine. Stimulants The stimulant medications used to treat ADHD are effective by increasing levels of certain brain chemicals (called neurotransmitters). This