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Disease duration, processing speed, and IBT perceptions were unique predictors of IBT performance in the MS group within a multivariate model. Persons with MS present with poorer IBT performance compared with HCs, which can limit participation. Processing speed and patient perceptions of IBT use and skills should be considered in technology design and training to improve the capabilities of persons with MS to use IBT for everyday living. (PsycInfo Database Record (c) 2021 APA, all rights reserved). Persons with MS present with poorer IB