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Objective To explore the significance of chromosome 6 aberrations for the occurrence and prognosis of hematopathies. Methods Clinical data and the cytogenetic results of 99 patients with hematopathies and aberrations of chromosome 6 were analyzed. Results The patients mainly had acute lymphoblastic leukemia (ALL), lymphoma, multiple myeloma, and myelodysplastic syndrome. ALL was the most common among the selected disorders. Based on their main abnormalities, ALL patients were divided into +6/-6, 6p and 6q groups. No significant differen