https://www.selleckchem.com/Androgen-Receptor.html
The expression of high-mobility group box 1 (HMGB1) in trophoblasts is elevated, which contributes to the development of preeclampsia. Thus, this study aimed to investigate the effect of glycyrrhizin, a natural HMGB1 inhibitor, on the development of preeclampsia. Preeclampsia was induced in pregnant Lewis rats through oral administration of L-NAME (50mg/kg/day) on gestational day (GD) 13-19. Glycyrrhizin (10, 30, or 60mg/kg/day) was given by oral gavage on GD 10-19. Systolic blood pressure (SBP), diastolic blood pressure (DBP), 24-hour