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Furthermore, genome wide association studies have found polymorphisms in glutamate receptor and transporter genes that are associated with migraine. The role of peripheral glutamate signalling in the onset and maintenance of migraine is not completely elucidated and future studies are still needed to confirm its role in migraine pathogenesis. The role of peripheral glutamate signalling in the onset and maintenance of migraine is not completely elucidated and future studies are still needed to confirm its role in migraine pathogenesis. Hyp
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