https://www.selleckchem.com/products/ml351.html
BackgroundEndothelial activation and microvascular dysfunction are key pathogenic processes in severe malaria. We evaluated the early role of these processes in experimentally induced P. falciparum and P. vivax infection.MethodsParticipants were enrolled in Induced Blood Stage Malaria clinical trials. Plasma osteoprotegerin, angiopoietin-2 and von Willebrand Factor (vWF) were measured as biomarkers of endothelial activation. Microvascular function was assessed using peripheral arterial tonometry (PAT) and near infrared spectroscopy (NIRS)
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