https://www.selleckchem.com/pr....oducts/ro-31-8220-me
Pancreatic islets are exposed to strong pro-apoptotic stimuli inflammation and hyperglycemia, during the progression of the autoimmune diabetes (T1D). We found that the downregulated by inflammation in the T1D prone NOD (non-obese diabetic) mouse model. The aim of this study is to determine the role of CDK11 in the pathogenesis of T1D and to assess the hierarchical relationship between CDK11 and Cyclin D3 in beta cell viability, since Cyclin D3, a natural ligand for CDK11, promotes beta cell viability and fitness in front of
Like
Comment
Share
