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ADHD Stimulant Medication Stimulants are used to treat symptoms like inattention and hyperactivity. They usually take effect within 30-60 minutes. They are the first line of treatment for people suffering from ADHD. Stimulants alter the activity of neurotransmitters such as dopamine and naradrenaline in the tiny synapses between neurons. They also improve communication between neurons. Methamphetamine Methamphetamine (also known as meth, crystal, ice or s