https://sumo-signal.com/index.....php/figuring-out-the
Aire is a transcriptional controller in medullary thymic epithelial cells (mTECs) modulating a collection of peripheral structure antigens (PTAs) and non-PTA mRNAs in addition to miRNAs. Also miRNAs exerting posttranscriptional control over mRNAs in mTECs, the composition of miRNA-mRNA networks may differ. Under decrease in Aire appearance, systems exhibited better miRNA diversity controlling mRNAs. Variants within the amount of 3'UTR binding sites of Aire-dependent mRNAs may portr
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