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Treating ADHD With Stimulant Medication Drugs that stimulate the brain, such as methylphenidate (Ritalin Concerta, Ritualin) and amphetamines (lisdexamfetamine, Adderall and Vyvanse) can help people manage their impulses and focus. Atomoxetine is a non-stimulant drug that increases brain neurotransmitters, dopamine and norepinephrine. The majority of adults with ADHD are treated with a combination therapy, medications and life-skills training. It is essential to select the right dosage and time for the medication in order to maximize its effectiveness. Stimulants