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OBJECTIVES AND DESIGN Data from the Italian national point-prevalence survey (PPS) of healthcare-associated infections (HAIs) were used to evaluate antimicrobial usage (AMU) in Italy and to identify targets for future interventions. METHODS The second Italian PPS was conducted in 2016 as part of the European PPS initiated by the ECDC. We compared these results with those of the first national survey, conducted in 2011. RESULTS An overall AMU prevalence of 44.5% (95% CI, 43.7-45.3) was estimated in 2016. No significant change in AMU prev
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