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The general strategy to hide almost arbitrary objects was discussed in the end. In principle, the numerical conformal coat engineered by the composite material proposed here could be broadly extended for objects with various geometries.Residual microtumors following surgical resection are the major cause for lethal cancer recurrence. However, it remains challenging to completely eliminate these residual microtumors. Here, we report an integrated strategy for image-guided surgical resection of tumors and intraoperative surface-enhanced