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In coming years, healing oligonucleotides may match the guarantee of tiny molecules and antibodies. Interestingly, within the 1980s when we developed chemical means of synthesizing oligonucleotides, nobody will have imagined that these very recharged macromolecules may become future medications. Certainly, the anionic nature and bad metabolic security of the all-natural phosphodiester backbone offered a major challenge for making use of oligonucleotides as healing medications. Thus, ty
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