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8% vs. 7.9%; P 0.001), acute HF (25.3% vs. 6.3%; P 0.001), and multiorgan failure (13.9% vs. 5.8%; P = 0.01. The association between AF and worse outcome was not modified by previous or concomitant use of anticoagulants or steroid therapy (P for interaction 0.05 for both) and was not related to stroke or bleeding events. Among hospitalized patients with COVID-19, a history of AF contributes to worse clinical course with a higher mortality and in-hospital events including new-onset AF, acute HF, and multiorgan failure. The