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Does ADHD Medication Work? When a person is given ADHD medication, they fret about how long the treatment will last and whether it will be effective. Here are some easy answers. Stimulants adjust brain chemicals that relay messages regarding attention and activity. Norepinephrine, dopamine and other brain chemicals are included. They are the first-line option for adults suffering from ADHD. 1. Stimulants Stimulants are among the most commonly prescribed drugs to treat ADHD. They alt