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hor(s). Transplantation Direct. Published by Wolters Kluwer Health, Inc.Primary graft dysfunction (PGD) is the leading cause of early death in lung transplant. Anelloviruses are small circular DNA viruses that have been noted to be present at elevated levels in immunosuppressed patients. They have been associated with both short- and long-term outcomes in lung transplant, and we hypothesized that anellovirus dynamics might be associated with the development of PGD. Methods We analyzed alphatorquevirus (ie, an anellovirus genus) levels in