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In this specific article, we evaluated the role and toxicity of RT in neuroblastoma customers. Anti-HER2 monoclonal antibodies (mAbs) such trastuzumab are effective for several phases of HER2-positive breast cancer (BC). But, intrinsic or acquired resistance to those medications may occur in an important amount of clients (pts) and, except for HER2 status, no validated predictive aspects of response/resistance are identified to date. This shortage is within part due to the maybe not yet fully elucidated process of